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Prepare the Beef Patties: In a large mixing bowl, combine the ground beef with Italian seasoning, garlic powder, salt, and pepper until evenly mixed. Form the mixture into four patties and set aside.
Toast the Buns: Preheat the broiler to medium-high. Lay the split buns on a baking sheet and toast them under the broiler until golden. Remove the tops and set aside.
Grill the Patties: Preheat your grill or grilling pan. Grill each patty for approximately 4-5 minutes per side, or until cooked to your desired level of doneness.
Heat the Pizza Sauce: While the patties are grilling, gently heat the pizza sauce in a saucepan over low heat, stirring occasionally.